You’ve probably heard of cannabidiol (CBD), the therapeutic compound in cannabis that has swept the health world off its feet. If you’re still wondering what all the rage is about, it’s time to brush up on your CBD facts.
Here are our top 10 important CBD oil facts To know!
1. CBD is a major component of cannabis but will not get you ‘high’
Hundreds of natural components make up the cannabis plant. THC and CBD are the most prevalent cannabinoids in the plant, but unlike THC, CBD has non-impairing effects.
THC is responsible for the psychoactive effects of cannabis. CBD does not bind to the same receptors in the body as THC which means it will not cause users to feel high. In fact, CBD has been shown to protect users against the psychoactive effects of THC. Those who have adverse reactions such as anxiety from consuming high-THC weed may find that CBD can ease those symptoms.
2. CBD oil has an extensive list of natural benefits
Research into CBD has unveiled numerous benefits from the compound. Users may find relief from many ailments naturally without relying on pharmaceuticals.
CBD oil natural Benefits are:
- Intractable pain
- Irritable Bowel Syndrome
- Parkinson’s (with more research in the near future, too)
3. CBD oil assists essential cannabinoids in the human body
Humans already produce their own cannabinoids naturally. Cannabinoids in the human body are called endocannabinoids, and cannabinoids from plant species are called phytocannabinoids.
Endocannabinoids play an important role in the regulation of appetite, mood, and other processes. The endocannabinoid system also affects inflammation in the body.
The endocannabinoid system doesn’t have to act alone and will respond to phytocannabinoids like CBD. Research shows that CBD works with two receptors in the body: CB1 and CB2. CB1 receptors are found throughout the brain, connective tissues, central nervous system, and other similar organs. CB2 receptors are found throughout the immune system, thymus gland, and other related areas.
Because these endocannabinoids regulate so many processes in the body, activating these receptors can mean relief from depression, anxiety, inflammation, and many other afflictions.
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4. CBD oil could help people with Clinical Endocannabinoid Deficiency (CECD)
Endocannabinoid deficiency is theorized to be an underlying factor in many immune system-related conditions. CECD occurs when the body produces an insufficient amount of endocannabinoids responsible for regulating various bodily functions. It is suggested that a deficiency in endocannabinoids causes a number of systems to not function properly.
Researchers have found support for this theory for many conditions, including migraines, irritable bowel syndrome, and fibromyalgia. While more research needs to be conducted, other conditions like multiple sclerosis, Parkinson’s, PTSD and more could be regulated with the use of CBD, eliminating the side effects from pharmaceuticals.
5. CBD works with other compounds to create the Entourage Effect
Cannabis is comprised of hundreds of compounds, and they work together when they stick together. Terpenes, flavanoids, cannabinoids and other compounds work synergistically to boost the effectiveness of the plant. This is known as the entourage effect.
Instead of using isolated CBD, whole-plant cannabis extracts keep these other compounds in place, allowing for stronger therapeutic effects. When a symbiosis between CBD, terpenes, and other compounds takes place, CBD can be more effective at relieving symptoms.
Having a clear understanding of the hemp oil facts will help users find the right type of CBD for their personal needs. CBD is sold in two forms: isolated CBD oil, and whole-plant CBD oil.
While its isolated form can ease many symptoms, it works better as a whole-plant extract because of the benefits from the entourage effect.
Terpenes are organic compounds found in the little hairs of cannabis. They make up the distinct smells and tastes of the plant in unique combinations depending on the strain.
When terpenes synergize with other cannabinoids, predominantly CBD, they can pass through the blood-brain barrier easier, which enhances their effects.
6. CBD and THC work differently to manage pain
Both THC and CBD can help people manage pain, but they do not work the same way. Knowing this CBD oil fact can help you take better control over your pain.
Neuropathic pain, associated with tingling, numbness and shooting, burning pains, may be suppressed by the use of CBD. This also goes for inflammation. THC, on the other hand, yields better results with spastic pain and cramps.
Those wanting to use cannabis to relieve their symptoms of spastic pain may want to go for something with THC. If they do not like the psychoactive effects of THC, using it in combination with CBD can be a more effective alternative because CBD can counteract the negative responses to THC.
7. CBD can be taken orally, sublingually, topically, or through inhalation
Users do not have to smoke or vape in order to get the benefits of CBD. There are many ways to administer cannabidiol, and they all work differently.
Ingesting CBD oil or CBD-infused foods is a convenient delivery method. Eating CBD means it first must travel through the digestive system where it is broken down in the liver. This reduces the concentration of cannabidiol, but the addition of fatty acids may help to increase absorption and counteract this effect.
Sublingual administration means leaving a dose of CBD oil under the tongue for about a minute before swallowing. This bypasses the digestive system which breaks cannabidiol down, diluting the concentration. When taking CBD sublingually, effects can be felt within minutes as the cannabidiol enters the bloodstream immediately.
CBD can also be taken topically, or through the skin. This method works better for targeted pain relief like sore muscles and achy joints. Topicals should have high CBD content to make up for the portion that does not cross the skin barrier.
CBD can also be smoked or vaped, and the effects are felt almost immediately. The lungs have a large surface area capable of absorbing more cannabidiol and delivering it to the bloodstream quickly.
Many growers have created low THC, high CBD strains for people seeking therapeutic effects. Keep in mind though, CBD leaves the bloodstream quicker when it is inhaled, so the effects will last a shorter amount than other methods.
8. CBD oil may shrink tumors by affecting different neurotransmitters
One of the most promising cannabis oil facts is its potential to shrink tumors by acting on different neurotransmitters. CBD has been shown to work as an allosteric modulator, which means it indirectly influences receptors.
CBD can manipulate the shape of certain receptors which changes the way they interact with neurotransmitters.
This is important because CBD oil has been shown to affect two receptors responsible for the regulation of pain: the mu and delta opioid receptors. Incorporating CBD into your routine can help target the mu and delta opioid receptors to manage chronic pain.
CBD can also act on the cannabinoid receptors, GPR55. Antagonizing these receptors can help regulate blood pressure and bone density, as well as anxiety.
Blockading activity of the GPR55 receptor may also be a crucial factor in cancer therapy. GPR55 has been found to play a significant role in cancer, as it can promote the growth of tumors.
When something acts on this, such as CBD antagonizing the receptors, tumors can shrink, especially in individuals with colorectal, breast, brain, and pancreatic cancer.
CBD oil also has been shown to activate TRPV1 and PPAR-gamma receptors. TRPV1 is responsible for the regulation of pain and inflammation, while PPAR-gamma receptors are known for their role in dopamine release, insulin resistance, and degradation of the beta-amyloid protein.
The beta-amyloid protein is associated with Alzheimer’s, and preventing degradation could provide valuable, life-changing effects to many.
9. CBD oil affects the same receptors as several prescription antidepressant drugs
High doses of CBD can also affect a subtype of serotonin receptors called 5-HT1A. These receptors in the brain are known for controlling mood, memory, and cognition. Activation of the 5-HT1A receptors plays a part in controlling anxiety as well. Human studies have shown that patients suffering from panic disorder have impaired 5-HT1A receptors.
Antidepressants such as MAOIs and SSRIs all work to signal the 5-HT1A receptors, either directly or indirectly. CBD may work in similar ways to activate receptors responsible for the regulation of mood and anxiety.
10. The first and only FDA-approved cannabidiol drug helps children with rare forms of epilepsy
Epidiolex is a prescription drug to control seizures in patients with Lennox-Gestaut syndrome or Dravet syndrome. These conditions cause severe and recurring seizures starting at a very young age. The drug can significantly reduce the occurrence of seizures, giving young children their lives back.
Subjects do not need to be diagnosed with a rare form of seizures to benefit from CBD for their seizures. The important CBD oil facts is becoming more well-known amongst the scientific communities, and acceptance as a prescription drug for severe seizures is a huge step.
The CBD and epilepsy connection has been known for a long time and the FDA approval is just the beginning.
“Representations regarding the efficacy and safety of [CBD Oil] have not been evaluated by the Food and Drug Administration. The FDA only evaluates foods and drugs, not supplements like these products. These products are not intended to diagnose, prevent, treat, or cure any disease. Click here [https://www.sciencedirect.com/science/article/abs/pii/S0304394018304099] to find evidence of a test, analysis, research, or study describing the benefits, performance or efficacy of [CBD Oil] based on the expertise of relevant professionals.”